Anti-ADRA2APolyclonalAntibody-一抗-抗體-蛋白與免疫
2023-10-29
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Anti-ADRA2A Polyclonal Antibody品牌：solarbio | 貨號(hào)：K008009P| 英文名稱(chēng) | Anti-ADRA2A Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | ADRA2;ADRAR;ZNF32;ADRA2R;ALPHA2AAR |
| 應(yīng)用 | WB IHC |
| 稀釋比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反應(yīng) | Human Mouse Rat |
| 蛋白分子量 | 49kDa |
| Gene ID | 150 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲(chǔ)存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human ADRA2A |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human ADRA2A |
| Subcellular Locations | Membrane |
| Swiss Prot | P08913 |
| 克隆類(lèi)型 | Polyclonal Antibody |
| 背景資料 | Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. |
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