Anti-CHMPolyclonalAntibody-一抗-抗體-蛋白與免疫
2023-10-29
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Anti-CHM Polyclonal Antibody品牌：solarbio | 貨號：K008000P| 英文名稱 | Anti-CHM Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | TCD;GGTA;REP-1;DXS540;HSD-32 |
| 應用 | IHC |
| 稀釋比例 | IHC 1:20-100. |
| 交叉反應 | Human |
| 蛋白分子量 | 73/12kDa |
| Gene ID | 1121 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human CHM |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human CHM |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P24386 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene. |
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