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貨號: WL02117 抗體名: caspas3/cleaved-caspase3 抗體 抗體英文名: caspas3/cleaved-caspase3 antibody 濃度: >1mg/ml 應用范圍: WB,IHC 宿主: 兔 適應物種: H,M,R 標記物: 無 克隆性: 否 保存條件: -20℃ 形態: 液體 亞型: IgG 規格: 50μl(>50μg)
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產品貨號WL02117產品名稱caspase3/cleaved-caspase3 Antibody預測分子量32,20 kDa別名CASP3; CPP32; CPP32B; SCA-1;active Caspase-3濃度>1 mg/ml免疫原合成caspase3/cleaved-caspase3多肽抗體來源兔特異性抗人、小鼠、大鼠克隆類型多克隆抗體產品應用WB; IHC成分親和純化抗體,20 mM PBS,150 mM NaCl,100 μg/ml BSA,50%甘油,NaN3<0.02%保存條件-20℃保存背景資料This Caspase-3 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. Caspase-3 is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins, such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP).
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