Anti-CTSCPolyclonalAntibody-一抗-抗體-蛋白與免疫
2023-10-29
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Anti-CTSC Polyclonal Antibody品牌：solarbio | 貨號：K007682P| 英文名稱 | Anti-CTSC Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | JP;HMS;JPD;PLS;CPPI;DPP1;DPPI;PALS;DPP-I;PDON1 |
| 應用 | WB IHC |
| 稀釋比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反應 | Human |
| 蛋白分子量 | 52kDa |
| Gene ID | 1075 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human CTSC |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human CTSC |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P53634 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. |
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