Anti-ASIPPolyclonalAntibody-一抗-抗體-蛋白與免疫
2023-10-29
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Anti-ASIP Polyclonal Antibody品牌：solarbio | 貨號：K004831P| 英文名稱 | Anti-ASIP Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | AGSW;AGTI;AGTIL;ASP;SHEP9 |
| 應用 | IHC |
| 稀釋比例 | IHC 1:50-100. |
| 交叉反應 | Human Mouse |
| 蛋白分子量 | 15kDa |
| Gene ID | 434 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | Recombinant protein of human ASIP |
| 性狀 | 液體 |
| Public Immunogen Range | Recombinant protein of human ASIP |
| Subcellular Locations | Secreted |
| Swiss Prot | P42127 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes. |
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