Anti-ALS2PolyclonalAntibody-一抗-抗體-蛋白與免疫
2023-10-29
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Anti-ALS2 Polyclonal Antibody品牌：solarbio | 貨號：K005033P| 英文名稱 | Anti-ALS2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | ALS2CR6;ALSJ;IAHSP;PLSJ |
| 應用 | WB |
| 稀釋比例 | WB 1:500-2000. |
| 交叉反應 | Human Mouse |
| 蛋白分子量 | 184kDa |
| Gene ID | 57679 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | Recombinant protein of human ALS2 |
| 性狀 | 液體 |
| Public Immunogen Range | Recombinant protein of human ALS2 |
| Subcellular Locations | Cytoskeleton Cytosol Endosome |
| Swiss Prot | Q96Q42 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. |
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