Anti-SF3B3PolyclonalAntibody-一抗-抗體-蛋白與免疫
2023-10-29
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Anti-SF3B3 Polyclonal Antibody品牌：solarbio | 貨號(hào)：K004347P| 英文名稱 | Anti-SF3B3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | RSE1;SAP130;SF3b130;STAF130 |
| 應(yīng)用 | WB IHC |
| 稀釋比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反應(yīng) | Human Mouse Rat |
| 蛋白分子量 | 136kDa |
| Gene ID | 23450 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲(chǔ)存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | Recombinant protein of human SF3B3 |
| 性狀 | 液體 |
| Public Immunogen Range | Recombinant protein of human SF3B3 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q15393 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron’s branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. |
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