Anti-Phospho-RPS6KB1-S240/244PolyclonalAntibody-一抗-抗體-蛋白與免疫
2023-10-29
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Anti-Phospho-RPS6KB1-S240/244 Polyclonal Antibody品牌：solarbio | 貨號：K006232P| 英文名稱 | Anti-Phospho-RPS6KB1-S240/244 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | S6 |
| 應用 | WB IP |
| 稀釋比例 | WB 1:500-2000. IP 1:50-100. |
| 交叉反應 | Human Mouse |
| 蛋白分子量 | 29kDa |
| Gene ID | 6194 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A phospho specific peptide corresponding to residues surrounding S240/244 of human RPS6KB1 |
| 性狀 | 液體 |
| Public Immunogen Range | A phospho specific peptide corresponding to residues surrounding S240/244 of human RPS6KB1 |
| Subcellular Locations | Cytosol Endoplasmic reticulum Nucleus |
| Swiss Prot | P62753 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. |
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