Anti-ARCPolyclonalAntibody-一抗-抗體-蛋白與免疫
2023-10-29
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Anti-ARC Polyclonal Antibody品牌：solarbio | 貨號：K008318P| 英文名稱 | Anti-ARC Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | Arg3.1 |
| 應用 | WB IHC |
| 稀釋比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反應 | Human Mouse Rat |
| 蛋白分子量 | 45kDa |
| Gene ID | 23237 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | Recombinant protein of human ARC |
| 性狀 | 液體 |
| Public Immunogen Range | Recombinant protein of human ARC |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q7LC44 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | Arc (for activity-regulated cytoskeleton-associated protein) is a growth factor and immediate early gene that is enriched in brain. Arc mRNA and protein levels are induced by neuronal activity, which is necessary to stimulate neuroplasticity, indicating a potential role for Arc in activity-dependent changes in dendrite function. Arc expression has been detected in neuronal cell bodies and dendrites in the hippocampus, amygdala, hypothalamus, striatum and cortex. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum. |
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