Anti-PTP4A2PolyclonalAntibody-一抗-抗體-蛋白與免疫
2023-10-29
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Anti-PTP4A2 Polyclonal Antibody品牌：solarbio | 貨號：K008224P| 英文名稱 | Anti-PTP4A2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | HH13;OV-1;PRL2;HH7-2;PRL-2;PTP4A;HU-PP-1;PTPCAAX2;ptp-IV1a;ptp-IV1b |
| 應用 | WB IHC |
| 稀釋比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反應 | Human Mouse Rat |
| 蛋白分子量 | 19kDa |
| Gene ID | 8073 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | Recombinant protein of human PTP4A2 |
| 性狀 | 液體 |
| Public Immunogen Range | Recombinant protein of human PTP4A2 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q12974 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. |
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