Description:
FGF-4 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-4 signals through the FGFR 1c, 2c, 3c, and 4. Recombinant human FGF-4 is a 19.7 kDa protein consisting of 182 amino acid residues.AA Sequence:GRGGAAAPTA PNGTLEAELE RRWESLVALS LARLPVAAQP KEAAVQSGAG DYLLGIKRLR RLYCNVGIGF HLQALPDGRI GGAHADTRDS LLELSPVERG VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFLP RLSource:
E.coliPurity:Greater than 95% by SDS-PAGE gel and HPLC analyses.Biological Activity:TheED
50as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 10
6units/mg.Cross Reactivity:Mouse, Rat, Human, N/A, PigResearch Interests:
| Angiogenesis/ Cardiovascular | | FGF Superfamily |
| Proliferation | | Stem Cells & Differentiation |
Country of Origin:USAResearch Use Only. Not for use in diagnostic or therapeutic procedures.
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